Is hydrosalpinx fluid cytotoxic?

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Is hydrosalpinx fluid cytotoxic?

Accumulation of oviductal fluid in the ampullar lumen as a result of occlusion of the infundibulum is referred to as hydrosalpinx. A low pregnancy rate (10%) after in-vitro fertilization (IVF) in hydrosalpinx patients and a relatively high incidence (50%) of abortions during the first trimester suggested that leakage of this fluid into the uterine cavity may exert a cytotoxic effect on the deve...

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Teratogenic effect of hydrosalpinx fluid in humans?

We read with great interest the manuscript by Chan et al. (2003) examining the teratogenicity of hydrosalpinx ¯uid (HF) using a whole rate embryo culture model. Mechanisms of HF formation and its effects on IVF and embryo transfer outcome have been recently reviewed (Ajonuma et al., 2002). Previous studies were conducted during early embryo development when HF that re¯uxed into the uterine cavi...

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Adverse effects of hydrosalpinx fluid on sperm motility and survival.

The negative impact of hydrosalpinx on IVF outcome is well recognized but some reports indicate that tubal infertility with hydrosalpinx is a heterogeneous entity and may have different effects on the outcome. The embryotoxic effects of hydrosalpinx fluid (HF) have been documented in mouse but not human embryos. This study examined the effects of HF on sperm motility and survival after various ...

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Ultrasound guided aspiration of hydrosalpinx fluid versus salpingectomy in the management of patients with ultrasound visible hydrosalpinx undergoing IVF-ET: a randomized controlled trial

BACKGROUND The aim of this study was to compare the efficacy of ultrasound guided aspiration of hydrosalpinx fluid at the time of oocyte retrieval with salpingectomy in the management of patients with ultrasound visible hydrosalpinx undergoing IVF-ET. METHODS One hundred and sixty patients with ultrasound visible hydrosalpinx were randomized into salpingectomy group and aspiration group using...

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ژورنال

عنوان ژورنال: Human Reproduction

سال: 1998

ISSN: 0268-1161,1460-2350

DOI: 10.1093/humrep/13.6.1620